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Migraines linked to rare genetic variants that could boost treatments | New Scientist

https://www.newscientist.com/article/2399865-migraines-linked-to-rare-genetic-variants-that-could-boost-treatments/?_ptid={kpdx}AAAAsp-yUkvwowoKcmJhNGYxWmNwZRIQbG85ZjBvbXNjN3VtNXRmdRoMRVg0T1lJVExZRUU2IiUxODIza2FnMDdnLTAwMDAzMnJrMmxwNnJzMWxsdHZyajFhOW40KhpzaG93VGVtcGxhdGVSN0I5REdGRE1PR0E2NzABOgxPVENPMkM2VzY0SEZSEnYtbG85ZXZoMHVtcmFuN2E5MFoOMTAzLjE4My45MS4xMTliA21hZmj8gvepBnAYeAQ

We know that migraines, which are recurrent and sometimes debilitating headaches, have some genetic basis, but the link with our DNA isn't entirely clear. Newly identified genetic variants could help in developing treatments, according to recent study.

Rare variants with large effects provide functional insights into the pathology of migraine subtypes, with and without aura.

Journal reference:

Nature Genetics DOI: 10.1038/s41588-023-01538-0

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